I’m Doing This For Debbie 1/30/2018

Do you ever get the feeling that you’re short changing yourself or that you have not done enough. Well when it comes to finding a living donor for my wife, that’s exactly how I am feeling now. I have posted, boosted post, made videos, and put the word out as best I know how but the fact is this, we still need a donor. I know what is needed but that’s the problem, I just cannot seem to get there. I think what is needed is a major connection with a very well known person who people will listen to and actually might consider donation. Now don’t get me wrong or take this the wrong way as I deeply appreciate everyone who has responded to my posts and those of you who actually called Indiana University for the interview I hold you in the highest regard. I especially appreciate everything that Lori Ann Crawford has done to help including making personal contact with Ann Marie Tiernon of Channel 13 Eyewitness News. Ann Marie posted one of my post on her Facebook page and for that I am forever grateful. But the fact remains that it obviously isn’t enough. I know that God has this, I believe that with all my heart but I still feel as if I am missing something.

The support from our church Flintwood Wesleyan and church family has been second to none. They have been there to pick me up every time I am down and out. I know that dialysis is the next step, and I guess acceptance is what I must do. But I cannot get it out of my head that dialysis is only temporary and that I know in my heart that out there somewhere there is a selfless, genuine, good hearted Christian who believes in the good book and the meaning of love thy neighbor. The fact is that the only and I do mean only way Debbie has to survive this thing is the sooner, to get a kidney plain and simple.  The sooner the better. I am hoping that by some miracle these post might happen to show up on a news feed of someone really important like say maybe Mike Pence or someone like that. I mean after all, Mike is from Columbus so who knows.

Debbie does not monitor any of my post at all, she has no Idea what I put out here but she does know that I would be lost without her and that living without her is not what I am looking forward to. So I will leave you with this thought, If it was your loved one who is in Debbie’s shoes, if you have done all that I have done would you have done enough? If the answer is no, I am open to suggestions!


I’m Doing This For Debbie 1/28/2018



Implantable Artificial Kidney Moves Closer to Reality
Written by Bob Curley on November 9, 2017

Scientists are developing an artificial kidney that can replicate the work of the real organs and potentially eliminate the need for dialsis.
Researchers at the University of California, San Francisco (UCSF), are developing an implantable artificial kidney that can closely replicate the functions of real kidneys.

If they are successful, the scientists’ work could help eliminate the need for dialysis.

Kidney transplants for patients with end-stage renal disease (ESRD) have a high rate of success.

About 93 percent of transplanted kidneys are still working after a year and 83 percent are functioning after three years.

But while more than 25,000 kidneys are transplanted each year, as of early 2016, more than 100,000 people were on the transplant waiting list in the United States.

Patients commonly wait five to 10 years for a suitable organ to become available.

Average life expectancy for dialysis patients is five to 10 years, although some have lived for decades.

However, dialysis — which filters out some (but not all) toxins from the bloodstream that would normally be eliminated by the kidneys — must be performed on a daily basis if done at home via peritoneal dialysis.

It requires three visits to a clinic weekly if performed via hemodialysis.

“The implantable bioartificial kidney is an alternative to dialysis and other externally wearable devices that would tether patients or limit their mobility,” Shuvo Roy, a professor in the UCSF Department of Bioengineering and Therapeutic Sciences and co-inventor of the device, told Healthline. “A live kidney transplant from a matching donor is still considered one of the best treatment options for ESRD, but unfortunately, there is shortage of organ donors that prevents transplants from being available to the vast majority of ESRD patients. Unlike transplants, our device will not require that patients be on immunosuppressive drugs to prevent rejection.”

Human trials of the device are about to begin.

Roy said the bioartificial kidney could eventually be used by the vast majority of the people now on dialysis and the kidney transplant list.

“This is a long-term solution, and any case where a kidney transplant is needed, our device will be a viable option,” said Roy.

How the device works
Roy leads The Kidney Project, a national research initiative centered on development and testing of a surgically implanted, freestanding bioartificial kidney that performs “the vast majority of the filtration, balancing, and other biological functions of the natural kidney.”

Powered by the body’s own blood pressure, the device does not require the external tubes or tethers associated with wearable artificial kidneys, such as that invented by Victor Gura of Cedars-Sinai Medical Center in Los Angeles. That device was tested on seven dialysis patients at the University of Washington Medical Center in Seattle in 2015.

The two-part implanted artificial kidney incorporates recent developments in silicon nanotechnology, which makes it possible to mass-produce reliable, robust, and compact filtering membranes.

The technology also has novel molecular coatings that protect the silicon membranes and make them blood-compatible.

“A hemofilter module processes incoming blood to create a watery ultrafiltrate that contains dissolved toxins as well as sugars and salts,” explained Roy. “Second, a bioreactor of kidney cells processes the ultrafiltrate and sends the sugars and salts back into the blood. In the process, water is also reabsorbed back into the body, concentrating the ultrafiltrate into ‘urine,’ which will be directed to the bladder for excretion.”

Patients with the implant may still be required to take hormonal supplements, however, as they currently do on dialysis, said Roy.

Development of alternatives to current treatments for kidney disease is “very important, since the outcomes of premature mortality and poor quality of life are common for the dialysis population, particularly for in-center hemodialysis,” Dr. Joseph Vassalotti, chief medical officer for the National Kidney Foundation, told Healthline.

The steps ahead
The Kidney Project is raising money to complete preclinical studies of the device modules and to build full-scale prototypes for the first round of human studies.

Initial clinical trials on the individual modules are expected to begin early next year.

Testing of a working prototype of the bioartificial kidney is slated for 2020.

“The long-term challenges center around keeping the device operating trouble-free after implantation beyond a few months,” said Roy. “Some problems won’t become clear until we do clinical trials.”

In addition to $6 million in government grants, the Kidney Project has received substantial donations from individuals in furtherance of its work to create an implantable artificial kidney.

“Their support is a testament to the acute need for a revolution in ESRD treatment, and the donations we have received are invaluable in allowing our research to progress,” said Roy.

In the future, scientists may be able to grow artificial kidneys.

In 2013, researchers, led by Melissa Little of the University of Queensland’s Institute for Molecular Bioscience, were able to grow a primitive kidney from human stem cells.

In 2016, researchers from the Salk Institute in California reported that they were able to grow nephron progenitor cells, which can differentiate into kidney tissue, in the lab.

Such research continues, but the ability to grow replacement organs remains a more distant dream than an implantable artificial kidney.



ealth News

I’m Doing This For Debbie 10/15/2017

This post is somewhat gonna be a difficult one for me on one hand. Don’t get the wrong idea because I am very blessed because today is the seventh wedding anniversary to my best friend. Seven years ago today on a balcony on a mountain side in Pigeon Forge Tennessee Debbie Patterson said “I Do” and made our life together complete. The official believe or not was a high school football coach who actually had a game that night so we made sure to schedule it so he wouldn’t be late. We have been together for eighteen years and married seven but it still seems like just yesterday that I walked into Ernie Stone Accounting at 8th and Washington street in Columbus Indiana and took her to lunch. My love for her has never weakened. I tell her that I love her at least three times each and every day and I have ever since we met eighteen years ago. She is who I think of when I wake up in the morning until I close my eyes at night. Yes it’s our seventh wedding anniversary and the last seven years of marriage and last eighteen years of our total relationship have been nothing less than fantastic in my opinion and I would change very little of it. But….yep there is a but. Don’t you just hate it when there has to be a “but” thrown in there? I know I do. But, this will probably be the last good anniversary we have and the last good year too. Because you see, Debbie, the love of my life, my very best friend, the one who I would never ever let down, desert, or walk away from. She and my daughter are the only ones I would walk on hot coals or take a bullet for. Debbie Patterson has Polycystic Kidney Disease, and I have absolutely no way that I can help here other than support and desparately trying to find her a donor. But if she does not get a kidney from a living donor soon….she will probably either be on dialysis.

If your are the least bit interested in helping Debbie out, please call Kelly at IU Transplant as she is the coordinator and be sure you let her know either when you talk to her or if you have to leave a message that you are interested in kidney donation for Debbie Patterson.. The phone number is…1-800-382-4602. She will do a phone interview and process all the info you give her to see if you are qualified. If by chance you are qualified she will send you a testing packet and give you the info as to how to proceed with testing to see if you are a match. Please, please, please share this post.